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COURTE PRESENTATION
J'ai précédemment effectué un stage post-doctoral dans le laboratoire d'Eve Marder à Brandeis University (Waltham, MA, USA) où j'ai étudié le rôle de la co-variation des propriétés de canaux ioniques dans l'activité du système stomatogastrique de crustacés. J'avais auparavant effectué ma thèse sous la direction de Pierre Vincent à l'Université Pierre et Marie Curie (Paris) où nous avions combiné l'imagerie par fluorescence de l'AMPc avec les enregistrements électrophysiologiques pour étudier la modulation des canaux ioniques sensibles au potentiel par la voie de l'AMPc. J'ai effectué le reste de mes études à Paris, à Montpellier et à Pau. PRECEDENTS LABOS
2002/2006 Laboratoire "Modulation of Neural Networks", Eve Marder, Brandeis University, Waltham, MA, USA Post-doctorant
1998/2002 Laboratoire "Neurobiologie des Processus Adaptatifs", UPMC, Paris, FRANCE Doctorant (Directeur de Thèse: Pierre Vincent)
1997/1998 Laboratoire "UNIC", Institut de Neurosciences Alfred Fessard, Gif sur Yvette, FRANCE Etudiant en Master (Directrice de Stage: Nicole Ropert)
LIENS
En plus des labos par lesquels je suis passé (ci-dessus), je vous donne ici les liens vers quelques labos qui font du boulot vraiment intéressant en Neurosciences :
- Dirk Bucher's lab (Whitney Laboratory for Marine Bioscience, St. Augustine, FA, USA).Système stomatogastrique de crustacés, dynamique de la fonction axonale. Electrophysiologie, anatomie.
- David Schulz's lab (University of Missouri, Columbia, MO, USA).Système stomatogastrique de crustacés (et autres), co-régulation de canaux, homéostasie de l'excitabilité. Electrophysiologie, biologie moléculaire.
- Stefan Pulver (Janelia Farm Research Campus, Ashburn, VA, USA).Etude des rythmes locomoteurs chez la larve de drosophile (l'asticot). Imagerie.
- Jeremy Niven's lab (University of Sussex, Brighton, UK). Evolution des systèmes nerveux, notamment chez les invertébrés. Electrophysiologie, modélisation.
- Harold Zakon's lab (University of Texas at Austin, Austin, TX, USA). Neuroéthologie de la communication électrique chez les poissons électriques. Electrophysiologie, modélisation.
PUBLICATIONS :- 2021 - Goaillard JM, Marder E.
Ion Channel Degeneracy, Variability, and Covariation in Neuron and Circuit Resilience Annual Review of Neuroscience, 44 : 335-357 - 2021 - Haddjeri-Hopkins A, Tapia M, Ramirez-Franco JJ, Tell F, Marqueze B, Amalric M, Goaillard JM.
Refining the Identity and Role of Kv4 Channels in Mouse Substantia Nigra Dopaminergic Neurons eNeuro - 2020 - Goaillard JM, Moubarak E, Tapia M, Tell F.
Diversity of axonal and dendritic contributions to neuronal output Frontiers in Cellular Neuroscience, 13 : 570 - 2019 - Moubarak E, Engel D, Dufour M, Tapia M, Tell F, Goaillard JM.
Robustness to axon initial segment variation is explained by somatodendritic excitability in rat substantia nigra dopaminergic neurons. Journal of Neuroscience, 39 : 5044-5063 - 2019 - Baudot P, Goaillard JM, Bennequin D, Tapia M.
Topological Information Data Analysis Entropy, 21 - 2018 - Tapia M, Baudot P, Formisano-Treziny C, Dufour M, Temporal S, Lasserre M, Marqueze B, Gabert J, Kobayashi K, Goaillard JM.
Neurotransmitter identity and electrophysiological phenotype are genetically coupled in midbrain dopaminergic neurons Scientific Reports, 8 : 13637 - 2015 - Hammond C, Debanne D, Goaillard JM.
Somato-dendritic processing of postsynaptic potentials II. Role of sub-threshold depolarizing voltage-gated currents Cellular and molecular neurophysiology - 2015 - Hammond, Goaillard JM, Debanne D.
Somato-dendritic processing of postsynaptic potential III. Role of high-voltage-activated depolarizing currents Cellular and molecular neurophysiology - 2015 - Hammond, Goaillard JM, Debanne D, Gaiarsa JL.
Synaptic plasticity Cellular and molecular neurophysiology - 2014 - Goaillard JM, Dufour M.
The pros and cons of degeneracy Elife, 3 : e02615 - 2014 - Dufour M, Woodhouse A, Goaillard JM.
Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development Journal of Neuroscience Research, 92 : 981-999 - 2014 - Mlayah-Bellalouna S, Dufour M, Mabrouk S, Mejdoub, H, Carlier E, Othman H, Belghazi M, Tarbe M, Goaillard JM, Gigmes D, Seagar M, El Ayeb M, Debanne D, Srairi-Abid N.
AaTX1, from Androctonus australis scorpion venom: Purification, synthesis and characterization in dopaminergic neurons Toxicon, 92 : 14-23 - 2014 - Marqueze B, Mailfert S, Rouger V, Goaillard JM, Marguet D.
Physiological epidermal growth factor concentrations activate high affinity receptors to elicit calcium oscillations PLoS One, 29 : e106803 - 2014 - Dufour M, Woodhouse A, Amendola J, Goaillard JM.
Non-linear developmental trajectory of electrical phenotype in rat substantia nigra pars compacta dopaminergic neurons eLife, 2014 Oct 20 - 2012 - Amendola J, Woodhouse A, Martin-Eauclaire MF, Goaillard JM.
Ca²⁺/cAMP-sensitive covariation of I(A) and I(H) voltage dependences tunes rebound firing in dopaminergic neurons Journal of Neuroscience, 32 : 125-132 - 2012 - Goaillard JM, Groc L, Lévi S, Mantegazza M, Matifat F, Morel JL, Baron-Forster A.
The 22nd ion channel meeting, september 2011, france Channels (Austin), 6 : 149-153 - 2011 - Bucher D, Goaillard JM.
Beyond faithful conduction: short-term dynamics, neuromodulation, and long-term regulation of spike propagation in the axon Progress in Neurobiology, 94 : 307-346 - 2011 - Goaillard JM.
Neural networks: more about flexibility than synaptic strength Current Biology, 21 : R276-278 - 2010 - Goaillard JM, Taylor AL, Pulver SR, Marder E.
Slow and persistent postinhibitory rebound acts as an intrinsic short-term memory mechanism Journal of Neuroscience, 30 : 4687-4692 - 2010 - Goaillard JM.
Immature brains don't need GABA to get 'hyper'-excited. Journal of Physiology, 588 : 7-8 - 2009 - Goaillard JM, Taylor AL, Schulz DJ, Marder E.
Functional consequences of animal-to-animal variation in circuit parameters Nature Neuroscience, 12 : 1424-1430 - 2009 - Taylor AL, Goaillard JM, Marder E.
How multiple conductances determine electrophysiological properties in a multicompartment model Journal of Neuroscience, 29 : 5573-5586 - 2007 - Schulz DJ, Goaillard JM, Marder E.
Quantitative expression profiling of identified neurons reveals cell-specific constraints on highly variable levels of gene expression Proc Natl Acad Sci U S A, 104 : 13187-13191 - 2007 - Cudmore RH, Goaillard JM, Debanne D.
Inhibition facilitates depression. Journal of Physiology (London), 585 : 323 - 2006 - Marder E, Goaillard JM.
Variability, compensation and homeostasis in neuron and network function Nature Reviews Neuroscience, 7 : 563-574 - 2006 - Goaillard JM, Marder E.
Dynamic-clamp analyses of cardiac, endocrine and neural function Physiology (Bethesda), 21 : 197-207 - 2006 - Schulz DJ, Goaillard JM, Marder E.
Variable channel expression in identified single and electrically coupled neurons in different animals. Nature Neuroscience, 9 : 356-362 - 2006 - Le T, Verley DR, Goaillard JM, Messinger DI, Christie AE, Birmingham JT.
Bistable behavior originating in the axon of a crustacean motor neuron. Journal of Neurophysiology, 95 : 1356-1368 - 2004 - Goaillard JM, Schulz DJ, Kilman VL, Marder E.
Octopamine modulates the axons of modulatory projection neurons. Journal of Neuroscience, 24 : 7063-7073 - 2003 - Goaillard JM, Marder E.
Exciting guts with GABA Nature Neuroscience, 6 : 1121-1122 - 2002 - Goaillard JM, Vincent P.
Serotonin suppresses the slow afterhyperpolarization in rat intralaminar and midline thalamic neurones by activating 5-HT(7) receptors. Journal of Physiology, 541 : 453-465 - 2002 - Laurent A, Goaillard JM, Cases O, Lebrand C, Gaspar P, Ropert N.
Activity-dependent presynaptic effect of serotonin 1B receptors on the somatosensory thalamocortical transmission in neonatal mice. Journal of Neuroscience, 22 : 886-900 - 2001 - Goaillard JM, Vincent P, Fischmeister R.
Simultaneous measurements of intracellular cAMP and L-type Ca2+ current in single frog ventricular myocytes. Journal of Physiology, 530 : 79-91
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